Jan Post – Hyvaa uutta vuotta!

         January (Tammikuu) 2024

Alzheimer’s 101 – Impact on the Brain

Did you know that someone in America develops Alzheimer’s disease every 65 seconds?

Today there are ~7 million Americans living with Alzheimer’s. If no cure or significant medical breakthrough is made, this statistic is projected to double to 13 – 16 million Americans by 2050, and individuals will be developing the disease every 33 seconds (compared to every 65 seconds today).

In the short period of time that I’ve had a direct connection to Alzheimer’s, I’ve learned how devastating the disease is. While a person can look completely “normal” and “healthy” on the outside, Alzheimer’s is slowly deteriorating the individual’s brain.

How exactly does Alzheimer’s impact the brain?

At a high-level, Alzheimer’s leads to nerve cell death and tissue loss throughout the brain. This impairs the brain’s functioning and size. The disease starts in the hippocampus section of the brain, a crucial region for memory and learning. Over time, Alzheimer’s affects areas in the cerebral cortex, which is responsible for language, reasoning, and social behavior. Eventually, many other areas of the brain are damaged and stop working normally.

Source: AD_500.png (1043×834) (nih.gov)

Scientists believe nerve cell death is caused by the formation of abnormal protein clumps called beta-amyloid plaques and tau tangles. Plaques and tangles build up, disrupt communication between brain cells, and contribute to the progressive cognitive decline seen in Alzheimer’s patients.

Plaques and tangles, which are the blue-shaded areas in the photo below, spread through the cortex in a predictable pattern. As the disease progresses, the person with Alzheimer’s gradually loses their ability to live and function independently. The disease is ultimately fatal, though the rate of progression varies. On average, a person with Alzheimer’s lives four to eight years after diagnosis, but can live as long as 20 years, depending on various factors.

Source: What is Alzheimer’s Disease? Symptoms & Causes | alz.org

Early diagnosis is critical. While there currently is no cure, there are medications that can slow the progression of Alzheimer’s. Early diagnosis allows the medications to be more effective.

In next month’s blog post, I’ll talk about Alzheimer’s symptoms.

Next Up: Ask a Finn, featuring the leader of our #GramFam, my dad.

January Raffle

This month’s raffle is for TWO TICKETs to the Boston Celtics game against the Detroit Pistons on Monday March 18, 2024. All proceeds will go directly to the Alzheimer’s Association.

These tickets were generously donated by  Charlie Noonan. Charlie was my AAU basketball coach in high school and has been a mentor throughout my adulthood.

Charlie is president of BCG Connect (BCG Connect | Creative Marketing for Fundraisers), which is headquartered in Wilmington, MA.

To enter the raffle, please follow the steps below:

  • Follow the link to our Miles for Memories Team page: ALZ Fundraising Page
  • Click the ‘Donate to the Team’ link
  • Under ‘Team Gifts’, click ‘Donate to the Team’
  • A $10 donation will result in 1 raffle entry. Additional $10 increments will result in additional raffle entries (example: $50 donation = 5 entries to the Jan raffle).
  • Under the ‘Donor Recognition’ section, type “Name – January Raffle” (example: Amanda Grammel – January Raffle).
  • The deadline to enter the January raffle will be Friday February 16. The raffle winner will be announced in the February blog post.
  • Good Luck!! And Go Celts!

Charlie’s close family friend, Louise, was diagnosed with Alzheimer’s. Your generous donation will provide critical funds for the Alzheimer’s Association to provide care and support to Louise, her family, and all those who are battling this devastating disease.

Thank you for your support! See you all in February!

Sources

“Alzheimer’s Disease Facts and Statistics.” Fisher Center for Alzheimer’s Research Foundation, http://www.alzinfo.org/understand-alzheimers/alzheimers-disease-facts-and-statistics/. Accessed 28 Jan. 2024.

“Brain Tour.” Alzheimer’s Disease and Dementia, http://www.alz.org/alzheimers-dementia/what-is-alzheimers/brain_tour. Accessed 28 Jan. 2024.